The answer is that it completely depends on the towelettes—and on the face wash you're used to as well. Cleansing wipes are just as varied as more traditional cleansers, so you should think about what makes a cleanser worthwhile or effective for you, then find a portable cloth version of that. If acne control and oiliness are an issue for you, something like The Body Shop Tea Tree Cleansing Wipes would probably be a good match. On the other hand, if brightening or exfoliating cleansers are your favorites, a product along the lines of Ole Henriksen Truth To Go Vitamin C Wipes might deliver better results for you. And if you're more a simple Cetaphil and water fan, try a gentle version like Pond's Original Fresh Wet Cleansing Towelettes.